Publications  
 
 


Chang LW, Fontaine BR, Stormo GD and Nagarajan R. PAP: A comprehensive workbench for mammalian transcriptional regulatory sequence analysis. Mol Nucleic Acids Res. May 21 (Epub ahead of print), 2007.

Link DC, Kunter G, Kasai Y, Zhao Y, Miner T, McLellan MD, Ries RE, Kapur D, Nagarajan R, Dale DC, Bolyard AA, Boxer LA, Welte K, Zeidler C, Donadieu J, Bellanne-Chantelot C, Vardiman JW, Caligiuri MA, Bloomfield, CD, Dipersio JF, Tomasson MH, Graubert TA, Westervelt P, Watson M, Shannon W, Baty J, Mardis ER, Wilson, RK and Ley TJ. Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia. Blood, May 9 (Epub ahead of print), 2007.


Sharma MK, Mansur DB, Reifenberger G,Perry A, Leonard JR, Aldape KD, Albin MG, Emmett RJ, Loeser S, Watson MA, Nagarajan R and Gutmann DH. 2007. Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin. Cancer Res. Feb 1:67(3):890-900, 2007.

Chang, L. W., Nagarajan, R., Magee, J. A., Milbrandt, J., and Stormo, G. D., A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles. Genome Res, 16, 405-413, 2006.


Le, N., Nagarajan, R., Wang, J.Y., Svaren, J., LaPash, C., Araki, T., Schmidt, R.E., Milbrandt, J., Nab proteins are essential for peripheral nervous system myelination. Nat NeuroSci, 8, 932-940, 2005..


Le N, Nagarajan R, Wang JY, Araki T, Schmidt RE and Milbrandt J. Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination. Proc Natl Acad Sci USA Feb 15;102(7) :2596-2601, 2005.


Walter, M. J., Park, J. S., Lau, S. K., Li, X., Lane, A. A., Nagarajan, R., Shannon, W. D., and Ley, T. J. Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures. Mol Cell Biol 24, 10882-10893,2004.


Nagarajan R., Ahmed, M. and Phatak, A. Database Challenges in the Integration of Biomedical Data Sets. In Proceedings of VLDB Conference, Toronto, Canada, August 2004. Database Challenges in the Integration of Biomedical Data Sets


Young, A., Nagarajan, R., and Longmore, G. Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway. Oncogene 22, 7209-7217, 2003.


Nagarajan, R., Le, N., Mahoney, H., Araki, T. and Milbrandt, J. Deciphering peripheral nerve myelination by using Schwann cell expression profiling. Proc Natl Acad Sci U S A 99, 8998-9003, 2002.


Modur, V., Nagarajan, R., Evers, B. M., and Milbrandt, J. FOXO proteins regulate TRAIL expression: Implications for PTEN mutation in prostate cancer. J Biol Chem 25, 47928-37,2002.


Gutmann, D. H., Hedrick, N. M., Li, J., Nagarajan, R., Perry, A., and Watson, M. A. Comparative gene expression profile analysis of neurofibromatosis 1- associated and sporadic pilocytic astrocytomas. Cancer Res 62, 2085-91, 2002.


Araki, T., Nagarajan, R., and Milbrandt, J. Identification of genes induced in peripheral nerve after injury. J Biol Chem 276, 34131-41,2001.


Nagarajan R, Svaren J, Le N, Araki T, Watson M, Milbrandt J. EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron 30:355-368, 2001.


Tourtellotte WG, Nagarajan R, Bartke A, Milbrandt J. Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis. Mol Cell Biol 20:5261-5268, 2000.

Tourtellotte WG, Nagarajan R, Auyeung A, Mueller C, Milbrandt J. Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice. Development 126:5061-5071, 1999.